August 2006 Vol Issue

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Hepatobiliary Complications of Inflammatory Bowel Disease

by Jorge L. Herrera
"Hepatobiliary complications of IBD are not the most common cause of abnormal liver tests in patients with IBD, particularly when the liver enzyme elevation is in a hepatocellular pattern," writes Dr. Herrera. His paper advises clinicians to use a systematic approach to exclude common causes of liver diseases that are unrelated to IBD.

An Overview of Expanded Newborn Screening for Inborn Errors of Metabolism

by Barbara Goodin
The American College of Genetics has recommended a core panel of inborn disorders for which newborns should be screened. This article provides an overview for inborn errors of metabolism - the screening process and the follow-up treatment. Also included are Internet resources for both physicians and families.

Successful Treatment of Retinal Neovascularization and Uveitis with Infliximab in a Patient with Crohn’s Disease

by Jared Z. Gold and Ramona O. Rajapakse
The report of a patient who first presented with an anterior uveitis, later developed symptoms of small bowel disease, posterior uveitis and retinal neovascularization. After colonoscopy, she was diagnosed as having Crohn’s Disease, was treated with infliximab which cured her uveitis.

by Sadiya Sarij and Seymour Katz

A 20-year-old male with Down’s syndrome presented with repeated episodes of painless melena and hematochezia over two months.

Hepatobiliary Disorders Associated with Inflammatory Bowel Disease

by Paul A. Feldman, Arie Regev and Jamie S. Barkin
A review of the hepatobiliary manifestations of IBD and the hepatotoxic effects of the medications used in its management. Also covered, the importance of routine monitoring of hepatic biochemical tests and an awareness of the implications and causes.