December 2007 Vol 0 Issue 12

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Disability in the Inflammatory Bowel Diseases: Impact of Awareness of the Americans with Disabilities Act

N.J. Procaccini and S.J. Bickston

The causes of inflammatory bowel disease (IBD) are multi-factorial. The findings in this study suggest that physicians may be able to identify patients who are at high-risk for unemployment or disability and target interventions on their behalf.


Pancreas Divisum: A Retrospective Review to Evaluate the Risk of Biliary Tract Neoplasms

Hala Fatima, Marie Malcolm, Stuart Sherman, Evan L. Fogel, Lee Mchenry, James L. Watkins, Thomas J. Howard, Thomas A. Ruffolo, Claudia E. Nugent, Ayman Abdel Aziz Hassan, Glen A. Lehman

Congenital anomalies of the biliary tree are established risk factors for cholangiocarcinoma (CCA). This review assesses the association of pancreas divisum (PD) with biliary tract neoplasms.


Beyond The Scope: The Hidden Images of Eating Disorders

Theresa Anderson

Due to the prevalence of GI symptoms in the majority of eating disorder patients, the gastroenterologists is often the initial medical contact for these patients. With these patients, avoiding judgement, criticism and blame is imperative. Working with a well-experienced and coordinated interdisciplinary team is the optimal treatment.


Subject Index / Author Index Volume XXXI

Departments Section

From the Literature


New research showing that probiotics can benefit health and positively impact the gastrointestinal tract was discussed at a symposium, "Probiotics: Applications in Gastrointestinal Health and Disease" held in conjunction with the 72nd Annual American College of Gastroenterology (ACG) Scientific Meeting.

Tuberculosis and IBD

In order to determine the incidence of active tuberculosis in an IBD population, compared with a general population before the availability of infliximab, a retrospective cohort study with the general practice research database from January 1988 to October 1997 was carried out. Ulcerative colitis and Crohn's disease subjects with a minimum of one-year of follow-up were matched to randomly selected subjects from the remaining population on year of birth, sex and primary care practice at a ratio of 1:4.

Recurrent Pancreatitis/Exocrine Insufficiency

To determine if worsening morphologic stages of chronic pancreatitis (CP) are associated with poor clinical outcomes, a retrospective analysis of 159 subjects with CP was performed. Pain was categorized as type A (intermittent acute), type B (continuous), or combined. Exocrine failure was defined by steatorrhea. Endocrine failure was characterized as diabetes mellitus. Complications were defined clinically.

Primary Prophylaxis of SBP

Norfloxacin has been shown to be highly effective in preventing SBP recurrence in cirrhosis, but its role in the primary prevention of this complication has been considered uncertain.

IBD and Pregnancy

To determine whether pregnancy outcomes differ between women with and without inflammatory bowel disease, and to determine what risk factors adversely affect outcomes, a cohort study of all pregnant women within the Northern California Kaiser Permanente membership between the years 1995 and 2002 was conducted. The records were abstractive of all pregnancies in women with IBD, and a random sample of pregnancy from age-matched women without IBD and risk factors were evaluated for spontaneous abortion, complications of pregnancy and adverse newborn events.

Inflammation as a Risk Factor for Neoplasia in Ulcerative Colitis

To determine whether severity of microscopic inflammation over time is an independent risk factor for neoplastic risk progression in UC, a cohort of patients with UC undergoing regular endoscopic surveillance for dysplasia were studied.

Risk of Colorectal Tumors with First Degree Relatives with Large Adenomas

A study aimed at quantifying the risk of colorectal adenomas and cancers using colonoscopic screening in first-degree relatives of patients with large adenomas was carried out as a case-controlled study.

Five-Year Colon Surveillance

A prospective study to measure incidence of advanced neoplasia in patients within 5.5 years of screening colonoscopy was carried out using 3,121 asymptomatic subjects, age 50 to 75 years between 1994 and 1997, who had screening colonoscopies in the Department of Veteran's Affairs.

Book Reviews

Clinical Nutrition in Gastrointestinal Disease

Buchman AL, Ed; SLACK, Incorporated, 2006
ISBN: 1-55642-697-6; $134.95

Most Gastroenterology training programs devote minimal time to nutrition course work, yet nutritional therapy is relevant to every facet of digestive disease. This comprehensive text, the effort of seventy experts in nutrition, is very appropriate for the trainee, as well as for all health care professionals seeking an update in clinical nutrition.

Pediatric Gastrointestinal and Liver Disease

3rd Edition; Wyllie R, Hyams JS and Kay M, Eds
Elsevier/Saunders, 2006; ISBN: 0721639240; $229

Pediatric Gastrointestinal and Liver Disease by Wyllie, Hyams, and Kay is the 3rd edition of a subspecialty text, whose expressed purpose is to provide a framework "to those providing care to children" with gastrointestinal and liver disease.