March 2007 Vol 0 Issue 3

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Irritable Bowel Syndrome: Diagnosis and Management

Deborah M. Bethards and Ann Ouyang

Irritable Bowel Syndrome (IBS) is a chronic condition which is frustrating to both the patient and the physician. This article gives some of the proposed pathophysiologic mechanisms, guidelines to help make a diagnosis and updated treatment regimens for control of IBS symptoms.


Prevention of Dysplasia and Cancer in Chronic Inflammatory Bowel Disease: A Role for Chemoprevention

Timothy L. Zisman and David T. Rubin

Recent data suggest a role for chemopreventive medications in reducing the risk of colorectal carcinoma (CRC) in patients with chronic inflammatory bowel disease (IBD). This article reviews and summarizes the available evidence regarding chemoprevention of colorectal cancer in patients with IBD.


Eosinophilic Gastrointestinal Disorders

Chris A. Liacouras

Dr. Liacouras' article covers the etiology, clinical features, diagnosis and treatment of three disorders that are defined in large part as eosinophilic gastrointestinal disorders.


Combining Diabetes and Gluten-free Dietary Management Guidelines

Cynthia Kupper and Laurie A. Higgins

Celiac disease in children with type 1 diabetes is estimated to be between five and 10 percent The authors offer practical tips for transitioning to a gluten-free, diabetic meal plan.


Case Report

Ari Wiesen and Samuel Davidoff

A case for you to solve.

Departments Section

Book Reviews

The Osler Medical Handbook, 2nd Edition

Piccini JP and Nilsson KR
Elsevier, Saunders, 2006
ISBN: 0323037488; $49.95

When I was first presented with the task of reviewing this book, I thought that a book with Sir William Osler's name on the cover would have to live up to high standards to be worthy of the use of his name.

Sleisenger and Fordtran's Gastrointestinal and Liver Disease, 8th Edition

Feldman M, Friedman LS and Brandt LJ (Editors)
Saunders Elsevier, 2006 (3112 pages 1074 illustrations)
ISBN: 1-4160-0245-6; $279

The 8th edition of this classic text is the first for which neither Drs. Fordtran nor Sleisenger had a first hand role in editing.

Clinical Dilemmas in Inflammatory Bowel Disease

Irving P, Rampton D and Shanahan F (Editor)
Blackwell Publishing Ltd., 2006
ISBN: 1-4051-3377-5; $59.95

The management of Inflammatory Bowel Disease (IBD) is a challenge for gastroenterologists and requires an approach combining both the science and the art of medicine.

From the Literature

New-Onset Diabetes and Pancreatic Cancer

A retrospective cohort study to estimate the incidence of pancreatic cancer subsequent to a new diabetes diagnosis was carried out, to include evaluation of factors associated with subsequent pancreatic cancer diagnosis.

Aminosalicylates in Prevention of Colon Cancer in UC

UC patients with dysplasia or CRC were matched with controls by disease duration, extent and age of diagnosis.

Disease Severity and Therapy for Chronic Hepatitis C

In patients with chronic hepatitis C, advanced fibrosis and cirrhosis are associated with lower rates of sustained virologic response (SVR) to Interferon-based therapy.

Post Colonoscopy U.C. Symptoms

Ulcerative colitis patients often report symptom flares after colonoscopy.

Probiotics in Antibiotic-Associated Diarrhea

To compare the efficacy of probiotics for the prevention of antibiotic-associated diarrhea (AAD), and the treatment of Clostridium difficile disease (CDD), based on the published, randomized controlled clinical trials, searches were made from 1977 to 2005.


Noninvasive Testing for Helicobacter Pylori

Infection due to Helicobacter pylori (H. pylori) is thought to occur during childhood, and accurate noninvasive testing is preferable to invasive testing performed by endoscopy and biopsy of the gastric mucosa. The authors of this study attempted to determine the accuracy of 13C-urea breath testing (UBT) and H. pylori stool antigen testing compared to endoscopy and biopsy.

Using Granulocyte Apheresis in Children with Ulcerative Colitis

Granulocyte apheresis is a technique which removes granulocytes and monocytes/macrophages from the blood, and it has been shown to improve the clinical symptoms of patients with ulcerative colitis (UC).

Medical Bulletin Board

News items of interest to the nation's gastroenterologists.

Topics in this section:
Cook Surgery Reports Significant Hospital Medicare Reimbursement for Promising New Fistula Repair Procedure

A Unique Test for the Rapid Detection of Shiga Toxins from Fecal Specimens Utilizing BioStar« OIA« Technology

FDA Approves LIALDA (mesalamine), the First Oral Once-Daily Mesalamine for Patients with Active, Mild to Moderate Ulcerative Colitis

Spirus Medical Launches Revolutionary System for Colonoscopy

Easy-to-Swallow Konsyl« Psyllium Capsules Provide a Convenient Source of Fiber at 25% the Cost of Competitive Offerings

Sandhill Scientific Announces Distribution Agreement for Noninvasive Liver Fibrosis Diagnostic Technology

Guidelines to Address Support of Families in the ICU