January 2008 Vol 0 Issue 1

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Antimycobacterial Therapy in Crohn's Disease: The End of a Long Controversy?

Laurent-Peyrin Biroulet, Christel Neut, Jean-Frédéric Colombel

The authors cite a number of studies in which antimycobacterial therapy is used to treat Crohn's disease, and give their conclusions of the results of the studies.


Metabolic Bone Disease in the Patient on Long-term Parenteral Nutrition

Cindy Hamilton, Douglas L. Seidner

This paper discusses many of the aspects of metabolic bone disease in patients on long-term parenteral nutrition.


Esophageal Lichen Planus and Hepatitis C: A Review of the Literature

Mohammad R. Taheri, Bryan Anderson, Thomas R. Riley III

This paper reports the first case in the literature of a patient with esophageal lichen planus related to HCV and gives a review of the literature.


Delayed Presentation of Traumatic Diaphragmatic Hernia Due to Stab Wound: Still Missing the Diagnosis

Kashyapkumar Patel, Avani Patel, Evelio Diaz Sirgado, Jonas Gintautas

A case of a delayed presentation of a diaphragmatic hernia due to a stab wound two years after the initial trauma.

Departments Section

From the Literature


It is generally understood that most cases of intussusception occur during infancy, and there appears to be an association with viral gastroenteritis, including Rotavirus infection. The authors of this study performed a prospective observational study of pediatric intussusception cases in 38 pediatric clinical sites in Switzerland as part of the Swiss Pediatric Surveillance Unit, an epidemiologic group which evaluates causes of childhood hospitalizations.

Food Allergy and Timing of Solid Food Introduction in Children

It is usually recommended that infants avoid solid food introduction until six months of age, in order to prevent the development of food allergies. However, the data to support this belief comes from small studies. The authors of this study used data from the German Infant Nutritional Intervention Program (GINI) which evaluated the development of eczema in two distinct regions of Germany.

Book Reviews

Colorectal Cancer: Evidence-Based Chemotherapy Strategies

Saltz LB, Editor
Humana Press, Totowa, New Jersey, 2007
ISBN: 1-58829-751-9; $ 99.50

This volume of approximately 280 pages serves as an excellent current monograph on colorectal cancer treatments.

Pancreas: Pathologic Practice and Research

Suda K , Editor
Karger, Basel, Switzerland, 2007
ISBN: 978-3-8055-8240-7; $180

This book is an excellent review of the embryology, pathogenesis and pathology of different pancreatic disorders. It touches several keen areas of pathology in various pancreatic disorders ranging from congenital anomalies to inflammatory and malignant problems with the pancreas.

Textbook of Hepatology: From Basic Science to Clinical Practice, Third Edition

Rodes J, Benhamou J-P, Blei AT, Reichen J,
Rizzetto M, Editors.
Blackwell Publishing, Malden, MA, 2007
ISBN: 978-1-4051-2741-7; $725

The third edition of the Textbook of Hepatology is a superb reference and sets the standard for hepatology textbooks in both content and quality.

Practical Pediatric Gastrointestinal Endoscopy

Gershman G. and Ament M.
Blackwell Publishing, Ltd. 2007.
ISBN: 9781405131933; $175

This text proposes to provide detailed instructions on all practical aspects of diagnostic and therapeutic endoscopy procedures in children.

Images of Memorable Cases: 50 Years at the Bedside

Fred HL and van Dijk HA
Long Tail Press/ Rice University Press 2007
ISBN: 978-0-89263-002-8
$85.50 (perfectbound), $160 (laminated textbook
binding), $165 (clothbound)

What ever happened to the art of physical diagnosis? It has been diluted by all of our technology. Dr. Fred and Mr. van Dijk have compiled 154 cases for the interested clinician to challenge himself/herself.

Medical Bulletin Board

T vs. B: Re-engineered Human T Cells Effectively Target and Kill Cancerous B Cells

Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia (ALL), according to researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).

New Healthcare Codes to Leverage Doctor-Patient Relationship Codes Will Mainstream Substance Use Screening and Intervention in Healthcare Settings

The White House Office of National Drug Control Policy (ONDCP) has announced the publication of new healthcare codes for substance abuse screening and brief intervention (SBI).

Researchers Find Significant Differences in Cancer Stage Presentation BetweenRural and Urban Patients

New research published in the November issue of The Journal of the American College of Surgeons shows that urban colorectal and lung cancer patients present at later stages of disease than rural patients do.

New Minimally Invasive Sampling Technique Allows for Earlier Diagnosis of Pancreatic Cancer

A new optical technology, coupled with routine endoscopy, may enable doctors to detect the subtle tell-tale traces of early pancreatic cancer, according to researchers at Northwestern University in Illinois.

From the Literature

Reactivation of Hepatitis B After HBe Antigen Seroconversion

A total of 133 HBeAg-positive, asymptomatic carriers who had undergone HBe seroconversion were studied.

Genotypes of Hepatitis B and Clearance of Hepatitis Be Antigen

In order to analyze clearance of HBeAg, taking into account age and genotype, a prospective cohort study of 1,158 Alaska native persons throughout Alaska were tested serially for HBeAg for median of 20.5 years and were genotyped.

HIV and Hepatitis C

The association of HIV and antiretroviral therapy (ART) with liver disease in patients with HCV infection were systematically reviewed from the epidemiologic perspective.