March 2008 Vol 0 Issue 3

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MAPping the Cause of Crohn's Disease or Simply Along For The Ride?

L. Campbell Levy, Kim L. Isaacs

The association between Crohn's disease (CD) and mycobacteria has evolved into intense debate. This article reviews the epidemiologic and clinical associations between M. paratuberculosis (MAP) and CD and the data available regarding the treatment of CD with MAP directed therapies.


Percutaneous Encoscopy in the Patient with Amyotrophic Lateral Sclerosis: Risk vs Benefit?

Nicholas J. Procaccini, Edward C. Nemergut

Seventy percent of patients with Amyotropic Lateral Sclerosis (ALS) develop difficulty in chewing or swallowing as their disease progresses and may benefit from gastrostomy tube placement to provide consistent nutrition. This article looks at the impact of nutrition on this patient population and the controversy regarding placement of gastrostomy tubes.


Suspected Asymptomatic Large Colon Lipoma: Biopsy?

Pavan Manchikalapati, John Levey

A case report of asymptomatic colon lipoma that was complicated by hemorrhage and bowel obstruction after endoscopic biopsy. This report reviews diagnostic methods and therapeutic options.


Hemosuccus Pancreaticus: A Rare Complication in Patients with Chronic Pancreatitis

Mazen Noureddin, Albert J. Chang, Michael Kline

Hemosuccus pancreaticus is rare, estimated to occur in about one in 1,500 cases of gastrointestinal hemorrhage. Presented here is case with endoscopic and radiographic images of hemosuccus pancreaticus in a patient with chronic pancreatitis due to alcohol abuse.

Departments Section

Book Reviews

Advanced Digestive Endoscopy: Comprehensive Atlas of High Resolution Endoscopy and Narrowband Imaging

Cohen J , Editor, 318 pp.
Blackwell Publishing, 2007
ISBN 978-1-4051-58886-2; $194.95

Advanced Digestive Endoscopy is a comprehensive textbook authored by fifty-two world renowned experts in this field.

Clinical Nutrition in Gastrointestinal Disease

Buchman A, Editor
SLACK, Incorporated, 2006
ISBN: 1-55642-697-6; $134.95

This comprehensive text, the effort of seventy experts in nutrition, is very appropriate for the trainee, as well as for all health care professionals seeking an update in clinical nutrition.

From the Literature

IBD and Ursodeoxycholic Acid Impact on Small-Duct PSC

A longitudinal cohort study was performed to characterize the clinical features of patients with small-duct primary sclerosing cholangitis (PSC), occurring with and without IBD and to determine the influence of IBD and to determine the effects of UDCA therapy on the course of liver disease.

Platelet Count as a Predictor of Gastroesophageal Varices in Cirrhosis

Current guidelines recommend EGD in patients with cirrhosis to screen for gastroesophageal varices (GEV).

Hepatic Nodules 2 cm or Smaller in Cirrhosis: Validation of Noninvasive Diagnostic Criteria for HCC

In order to prospectively evaluate the accuracy of contrast-enhanced ultrasound (CEUS) and dynamic MRI for the diagnosis of nodules 20 mm or smaller detected during ultrasound (US) surveillance, 89 patients with cirrhosis, without prior hepatocellular carcinoma (HCC)in whom US detected a small solitary nodule were studied.

Efficacy of Radiofrequency Ablation of Early Hepatocellular Carcinoma in Cirrhosis

If liver transplantation is not feasible, partial resection has been considered the treatment of choice for HCC in patients with cirrhosis.

Individualized Treatment for HCV Genotype 1 Patients

To evaluate the hypothesis that in HCV genotype patients, variable treatment duration individualized by first undetectable HCV RNA is as effective as standard 48 week treatment...

Fourteen Week vs. Twenty-Four Week Treatment for HCV Genotype II or III

To assess the concept that HCV patients with genotype 2/3 and rapid virological response (RVR) may have a 90% SVR rate after 14 weeks of treatment, 428 treatment-naÔve HCV RNA-positive patients with genotype 2 or 3 were enrolled.

Terminal Ileum BiopsiesóDiagnostic Value

Four hundred fourteen consecutive patients with terminal ileal biopsies were retrospectively reviewed.

MRI and Acute Pancreatitis

CT scan, especially contrast-enhanced (CECT), provides important information on the severity and prognosis of acute pancreatitis (AP). Magnetic resonance imaging (MRI) has become a useful tool as an alternative to CT in the assessment of AP.

Double-Balloon Enteroscopy in Refractory Sprue

In patients with refractory celiac disease in developed enteropathy-associated T-cell lymphoma (EATL), or ulcerative jejunitis, double-balloon enteroscopy allows examination of the small bowel to prospectively assess the value of this technique in patients with refractory celiac disease.

Medical Bulletin Board

World's Largest Diet-Cancer Study Confirms Current Advice on Alcohol

Experts at the American Institute for Cancer Research (AICR) welcomed the latest results from the world's largest study on diet and cancer. The new results, published online at the International Journal of Cancer, link excessive alcohol consumption to an increased risk of colon cancer.

Survey Shows Gender Differences are a Factor When Surgeons in Training Choose a Subspecialty

Many factors may influence whether a general surgery resident pursues a subspecialty as a career choice, but women think about lifestyle more than men.

bioLytical Laboratories: INSTITM HIV-1 Rapid Antibody Test to be Used in Research Study Conducted by McGill University AIDS Centre and Funded by CIHR

bioLytical Laboratories is pleased to announce the use of its 60-second rapid HIV test, INSTITM, in a research study entitled "Pro-active intervention to limit HIV transmission among MSM populations."

Study Data Show Asacol® (Mesalamine) is Effective in Treating All Extents of Ulcerative Colitis Including Isolated Proctitis

Findings Reinforce the Benefits of Asacol for Ulcerative Colitis Patients Data from two Phase III clinical trials support that Asacol, an oral, non-steroidal medication that belongs to the class of agents known as 5-aminosalicylic acids (5-ASAs), is an effective and well-tolerated treatment for patients with all extents of ulcerative colitis (UC), including isolated proctitis.

Nationwide Survey Reveals Differing Physician and Patient Perceptions Regarding Impact of Ulcerative Colitis on Patients' Lives

Authors Conclude Communication and Compliance Important for Addressing Challenges Uncovered in Survey.