July 2009 Vol XXXIII Issue 7

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When What Comes Out Is Way More Than What Goes In: Perineal Skin Care

Marilu Dixon

A note from the nutrition series editor, Carol Parrish: You might wonder what this article is doing in a nutrition series. I will tell you. For gut adaption to take place in the setting of a short gut, luminal nutrients must be ingested. Furthermore, for the clinician to determine efficacy of interventions on stool output and the patient's ability to maintain weight and hydration, the patient must be assessed eating and drinking the volume of food and fluid necessary to achieve that end. If the patient will not eat and drink for fear of, or because of, a sore bum, we are going nowhere.


Depression and Its Treatment

James Goodhand, David Rampton

Depression in patients with inflammatory bowel disease is double of that in the general population. Animal data suggest that intestinal inflammation may precipitate mood disorders by directly altering cerebral function. Does depression have a detrimental effect on IBD? This question remains controversial.


Nutritional Complications of Celiac Disease

Jennifer Autodore, Muralidhar Jatla

Celiac disease affects the absorptive capacity of the small intestine and can lead to specific nutrient deficiencies such as iron, calcium and folate. This article details these deficiencies and how best to treat them.


A case for you to solve.

Alexandra Guttierrez, Talha Malik

Departments Section

From the Literature

Gastroparesis Incidence and Natural History

To determine the incidence, prevalence and outcome of gastroparesis in the community, the Rochester Epidemiology Project was utilized, representing a medical records linkage system in Olmstead County, Minnesota. County residents with potential gastroparesis were identified.

Hyperglycemia, Helicobacter Pylori and Gastric Cancer

This study was performed to evaluate the impact of hemoglobin A1C levels on gastric cancer occurrence and their interaction with Helicobacter pylori.

Alcohol and Cigarette Smoking as Risk Factors for ERCP

Alcohol use and cigarette smoking are associated with various pancreatic diseases. In order to determine whether they are associated with post-ERCP pancreatitis (PEP), a retrospective, case-controlled study to determine if these activities increase the risk for same was carried out.

Increased ALT in Asymptomatic Chronic Hepatitis B Infection

A total of 217 asymptomatic patients with chronic HBV who were HBeAg-negative, anti-HBe antibody positive, with normal ALT levels, were followed. Spontaneous increases in ALT levels (ALT flared), were considered if they were greater than two-fold of the upper limits of normal and were accompanied by HBV DNA levels greater or equal to 10ˇ copies per milliliter, or a 100-fold increase from the previously measured levels.

Book Reviews

Principles of Clinical Gastroenterology

This first edition of Principles of Clinical Gastroenterology is edited by Tadataka Yamada, the author of the well-known Textbook of Gastroenterology. There are many contributing editors to this text including David Alpers, Anthony Kalloo, Neil Kaplowitz, Chung Owyang and Don Powell. The authors are renowned authorities in the field of gastroenterology. The text is based on a clinical approach to signs and symptoms of gastroenterological disorders covered in the Textbook of Gastroenterology.

Teaching Atlas of Abdominal Imaging

Doctors Harisighani and Mueller compiled the Teaching Atlas of Abdominal Imaging from classic cases presented at Massachusetts General Hospital Division of Abdominal Imaging radiology rounds. The atlas is a 530-page, well-bound, hardcover book in case-based format divided into abdominal organ systems with an additional section on the pelvis. Each of the 155 cases is about three pages long and is divided into two sectionsóthe specific case followed by a more general discussion.