January 2011 Vol XXXV Issue 1

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Dietary Interventions in Patients with Inflammatory Bowel Disease

Takayuki Yamamoto, Maki Nakahigashi, Abbi R. Saniabadi

In this article we review the current evidence for dietary constituents as risk factors for the development of IBD and critically discuss the reports on the efficacies of dietary and enteral interventions.


Nasal Bridle: Married to Your Tube

Krishna C. Gurram

New data has emerged suggesting that bridles may delay or decrease the need for percutaneous endoscopic gastrostomy (PEG) placement, and as a result, the 30-day mortality associated with it. This review describes the technique of bridle placement and the latest outcomes data.


Congenital Type 1 Choledochal Cyst in an Adult Male Presenting with Primary Invasive Cholangiocarcinoma

Sanjaya K. Satapathy, Jaydeep Kadam, Kostas Sideridis

We present a rare case of a patient with Type 1 choledochal cyst presenting with invasive cholangiocarcinoma.


Sahil Khanna, Amindra S. Arora

A case for you to solve

Departments Section

Book Reviews

Early Detection and Prevention of Colorectal Cancer

Early Detection and Prevention of Colorectal Cancer edited by Dr. Karen E. Kim is a hardcover book meant to be a comprehensive resource yet useful reference for practicing physicians in adult medicine or gastroenterology, as well as trainees and allied health professionals.

From the Literature

IL-28B as a Pre-Treatment Predictor of SVR in Genotype I HCV

To confirm the polymorphisms clinical relevance of IL-28B as associated with a two-fold distance in sustained virologic response (VR) to PEG Interferon-Alfa and Ribavirin therapy, intention to treat analysis was carried out on-treatment virologic response SVR.

Lymphocytic Enteropathy and Celiac Disease

A prospective study to determine the clinical, pathologic, and serologic spectrum of celiac disease in a general population was carried out by random sample of an adult general population (N = 1000), analyzed by upper endoscopy, duodenal biopsy, and serologic analysis of tissue transglutaminase (tTg) levels, endomysialantibody (EMA), when tTg was positive.

Medical Bulletin Board

Thioketal Nanoparticles: Researchers Develop Oral Delivery System to Treat Inflammatory Bowel Diseases

Researchers at the Georgia Institute of Technology and Emory University have developed a novel approach for delivering small bits of genetic material into the body to improve the treatment of inflammatory bowel diseases.

Merckís Investigational Medicine Boceprevir Achieved Significantly Higher SVR Rates In Treatment-Failure and Treatment-NaÔve Adult Patients with Chronic Hepatitis C Genotype 1 Compared to Control

Merck has reported that final results from two pivotal Phase III studies of boceprevir, its investigational oral hepatitis C protease inhibitor, demonstrated significantly higher sustained virologic response (SVR) rates in adult patients who previously failed treatment (treatment- failure; HCV RESPOND-2) and in adult patients who were new to treatment (treatment-naÔve; HCV SPRINT-2) for chronic hepatitis C virus (HCV) genotype 1 compared to control, the primary objective of the studies.