February 2012 Vol XXXVI Issue 2

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Nutrition Issues in Gastroenterology, Series #102

Celiac Disease: What Gluten-Free Means Today

Tricia Thompson

Currently, the only treatment for celiac disease is a gluten-free diet. While the gluten-free diet may be challenging at first, the learning curve is steep. It is essential that patients receive up-to-date timely and on-going counseling from a registered dietitian proficient in celiac disease and the gluten-free diet.

A Case Report

Cholangiocarcinoma Arising in Type IV Choledochal Cyst in a Patient with Pancreaticobiliary Maljunction: Case Presentation and Review of the Literature

Elie Aoun, Adam Slivka, Michael K. Sanders

Choledochal cysts are rare cystic dilations of the biliary tree of unclear etiology. Here we present a case of cholangiocarcinoma arising in a type IV choledochal cyst with a review of the literature.

Departments Section

Book Reviews

Acing the Hepatology Questions on the GI Board Exam: The Ultimate Crunch-Time Resource

This 260-page book is the second book in the series by Dr. Spiegel and was written with a focus on hepatology-related GI board exam questions. The book’s aims are to provide an emphasis on key concepts in liver disease. This knowledge will then guide both clinical practice and successful completion of the Internal Medicine GI board exam.

Controversies in Hepatology:The Experts Analyze Both Sides

The book "Controversies in Hepatology" edited by Donald M. Jensen is a 275-page book that presents the points and counterpoints of everyday challenges in the field of liver diseases. The authors present brilliant discussions in every chapter and figures and tables that are easy to read. More importantly; at the end of every presentation, the key points of the available information are displayed for the reader to compare the "pros" and "cons" of a particular diagnostic or therapeutic approach.

Inflammatory Bowel Disease: Diagnosis and Therapeutics (Second Edition)

Dr. Cohen has ensured that his textbook of inflammatory bowel disease (IBD) counts itself among the best overviews on the topic, while only rarely feeling dated in its content. Additionally, with a historical overview of IBD by Joseph Kirsner representing the foreword (in honor of his centennial birthday), this book opens with a personal and wise voice.

Crohn’s Disease: The Complete Guide to Medical Management

Crohn’s Disease: The Complete Guide to Medical Management offers a clear and comprehensive resource guide for gastroenterologists who manage patients with Crohn’ss disease. Through the efforts of its editors, Gary Lichtenstein and Ellen Scherl, as well as the input many nationally and internationally renowned experts in the field of inflammatory bowel disease (IBD), this 469- page book pragmatically reviews the epidemiology, clinical research, and medical therapies currently available to clinicians involved in treating and caring for patientsof all ages with Crohn?s disease.

From the Literature

Cap Polyposis Update In Reference to Therapy

Seven patients were diagnosed with cap polyposis at the Asian Medical Center between December 1999 and August 2010. All were women, with a median age of 42 years and all were histologically confirmed as having cap polyposis in specimens obtained by colonoscopic polypectomy.

Medical Bulletin Board

FDA Clears Apollo Endosurgery’s SuMO™

Endoscopic Tissue Access and Resection System SuMO System Allows Physicians to Perform Scarless Surgery to Remove Large Flat Pre-Cancerous Lesions During Colonoscopies and Upper Endoscopies

Merck Announces Initiation of Clinical Development Collaboration with Roche To Evaluate Investigational Combination Regimens for the Treatment of Chronic Hepatitis C Genotype 1 Infection

New Clinical Trial Will Evaluate an Investigational Therapeutic Regimen with VICTRELIS™ (boceprevir)

Lubiprostone Meets Primary Endpoint in Phase 3 Clinical Trial for Opioid-Induced Bowel Dysfunction (OBD)

Aim to File for Approval of Lubiprostone as First Oral Drug for Prescription-based Treatment of OBD Anticipate sNDA Filing in US in First Half of 2012

Signal Genetics Announces Publication of Meta- Analysis of its Colon Cancer Test-Previstage™ GCC Confirming Prognostic Capabilities in Patients with Colon Cancer

Signal Genetics, a privately held personalized medicine company focused on cancer, announced the presentation of a paper entitled "Guanylyl Cyclase C (GCC) Lymph Nodes (LN) Classification as a Prognostic Marker in Patients with Stage II Colon Cancer: A Pooled Analysis" at the 2012 American Society of Clinical Oncology Gastrointestinal Cancer Symposium held in San Francisco, CA January 21, 2012. The data from the paper demonstrate the value of implementing Previstage testing in patients with colorectal cancer to identify those patients at risk of relapse.