January 2014 Vol XXXVIII Issue 1
Frontiers in Endoscopy, Series #8
Advanced Imaging of the Gastrointestinal LumenEndoscopy has been the gold standard for the evaluation and management of a multitude of gastrointestinal pathologies ranging from premalignant lesions such as Barrett’s esophagus and colonic adenomas to inflammatory conditions such as ulcerative colitis and Crohn’s disease. In recent years there have been significant technological advances, such as optical magnification and high definition (HD) cameras, dye-based chromoendoscopy, electronic chromoendoscopy, confocal laser endomicroscopy, and nascent technologies such as endocytoscopy and molecular labeling. This review will describe the use of advanced endoscopic technologies, their basic risks and benefits, and their clinical applicability.
Unusual Causes of Abdominal Pain, #1
Abdominal Wall PainMagnesium is essential to many metabolic processes, yet hypomagnesemia is common in hospitalized patients, especially in the critically ill. With high morbidity and mortality rates reported in hypomagnesemic patients, prompt diagnosis and treatment is of utmost importance. This article will review magnesium basics including assessment tests, etiologies of hypomagnesemia and provide guidance on effective ways of treating magnesium deficiency.
Nutrition Issues in Gastroenterology, Series #125
Magnesium — So UnderappreciatedMagnesium is essential to many metabolic processes, yet hypomagnesemia is common in hospitalized patients, especially in the critically ill. With high morbidity and mortality rates reported in hypomagnesemic patients, prompt diagnosis and treatment is of utmost importance. This article will review magnesium basics including assessment tests, etiologies of hypomagnesemia and provide guidance on effective ways of treating magnesium deficiency.
Epidemiology of Gastrointestinal Cancers, #2
Changing Epidemiology of Esophageal Cancers Worldwide - What Do We Learn?Here we report the incidence of esophageal cancer (EC), the tenth most common and the eighth most deadly type of cancer worldwide with more than 80% of deaths in developing countries. The epidemiology of EC has undergone a dramatic downward shift worldwide in the last 30 years. The aim of this review is to summarize important epidemiological data that has widespread clinical implications.
A Case Report
Epiploic Appendagitis: Underappreciated, Easily Misdiagnosed and Often Masquerading as an Acute AbdomenDepartments Section
PPI Use in Infants for GERD
Proton pump inhibitors (PPIs) have been approved as a treatment of gastroesophageal reflux disease (GERD) symptoms in infants in children. Unfortunately, these drugs are often used to treat non-specific symptoms in infants without clear evidence of GERD. The authors of this study performed at randomized, double-blind, placebo-controlled trial at 3 centers in Australia, Germany, and the United Kingdom to determine the efficacy of the PPI, esomeprazole, versus placebo in the treatment of signs and symptoms possibly attributable to GERD.
Do Probiotics Help Colic?
Colic is a symptom of excessive infant crying and irritability that affects up to 20% of infants younger than 3 months of age. Its cause is unknown, and colic is a risk factor for child abuse and maternal mental health issues. Prior studies have suggested that infants with colic have a different intestinal microbial profile compared to those infants without colic. The authors of this study performed a systematic review and meta- analysis using databases that included MEDLINE, EMBASE, and the Cochrane Library. Articles were reviewed from 1950 to 2012, and studies were evaluated for infant characteristics, type of probiotic use, outcome measures, and adverse events.
FDA ADVISORY COMMITTEE RECOMMENDS APPROVAL OF TAKEDA’S INVESTIGATIONAL BIOLOGIC VEDOLIZUMAB
Takeda Announces Positive Vote on Vedolizumab to Treat Ulcerative Colitis and Crohn’s Disease
OLYMPUS INTRODUCES WORLD’S ONLY FORWARD-VIEWING CURVILINEAR ULTRASOUND GASTROVIDEOSCOPE
TGF-UC180J Provides the Potential for New Opportunities in EUS-Guided Treatment of Diseases in the GI Tract