April 2014 Vol XXXVIII Issue 4

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Frontiers in Endoscopy, Series #10

Evaluation and Management of Pancreatic Pseudocysts

Matthew E. Feurer, Douglas G. Adler

The management of pancreatic pseudocysts is complex and can range from simple observation to aggressive endoscopic and surgical interventions to treat symptomatic lesions. This manuscript will review the current evaluation and treatment of pancreatic pseudocysts.

A Case Report

Drainage of a Symptomatic Pancreatic Pseudocyst via a Fully Covered Self Expanding Metal Stent (FCSEMS)

Douglas G. Adler

Epidemiology of Gastrointestinal Cancers, #3

Gastric Cancer: A Global Perspective

Febin John, Janeesh Sekkath Veedu, C.S. Pitchumoni

Wide geographic variation exists in the incidence of Gastric Cancer, with a high incidence in the eastern parts of Asia and Europe, but rare in North America and Western Europe. Here we discuss dietary practices, effective Helicobacter pylori eradication, early diagnosis, endoscopy and target biopsies coupled with effective surgical procedures and their affect on outcomes.

Nutrition Issues in Gastroenterology, Series #128

Nutrition Update in Hepatic Failure

Joe Krenitsky

Advancements in the understanding of malnutrition and the limitations of traditional nutrition assessment have spurred the development of new methods of evaluating nutrition status that are particularly applicable to patients with cirrhosis. Here we discuss the importance of successfully combating malnutrition through the efforts of the entire healthcare team to educate patients and families, and the need for adequately designed research to investigate the effects of providing additional nutrition to cirrhotic patients with malnutrition on quality of life and other outcomes.

Unusual Causes of Abdominal Pain, #3

Unusual Causes of Abdominal Pain

George W. Meyer

A Case Report

Intrahepatic-Ductal Papillary Mucinous Neoplasm: A Real Disease Entity

Megha Kothari, Matthew Grossman, Gregory Haber

Departments Section

Book Reviews

Acing the IBD Questions on the GI Board Exam: The Ultimate Crunch-time Resource

This study guide is the third installment in the “Acing” series, which focuses on key inflammatory bowel disease (IBD) issues that will be covered on the gastroenterology board exam. This book is organized into three main sections: an overview of most common IBD subjects on the test; “Tough Stuff” vignettes that highlight IBD-related medical and surgical problems; and a “Crunch-Time” self-test with answers.

From the Pediatric Gastroenterology Literature

Which Children Need a Fundoplication?

Gastroesophageal reflux disease (GERD) symptoms in children can be difficult to detect, especially in infants, and the effect of pediatric patient age on performing an antireflux procedure (ARP) for GERD is not known. The authors of this study evaluated patient data retrospectively using the Pediatric Health Information System database which tracks treatment data from 41 United States children’s hospitals. In particular, ARP as treatment for GERD was examined in relation to initial or subsequent hospitalizations of pediatric patients. This patient group was compared to patients hospitalized for GERD without ARP being performed. Patient data was broken down by age (less than 2 months old, 2 to 6 months, 7 months to 4 years, and 5 to 17 years).

Are We Treating Crohn’s Disease in Children Correctly?

determine if therapy was controlling symptoms at one year. Patients from 28 pediatric gastroenterology centers in North America were enrolled and prospectively followed in an observational study to follow response to therapy.

From the Literature

Methotrexate Combined with Infliximab is Not More Effective than Infliximab Alone in Crohn’s Disease with Prednisone Induction Therapy

To evaluate the potential superiority of combination therapy over infliximab alone, a 50-week, double-blind, placebo-controlled trial was carried out to compare methotrexate and infliximab, with infliximab alone in 126 patients with Crohn’s disease (CD) who had initiated prednisone induction therapy (15 to 40 mg/ day), within the preceding six weeks.

Reduced Risk of Colorectal Cancer Ten Years After Colonoscopy

A population-based, case-controlled study of 3148 patients with a first diagnosis of colorectal cancer (CRC) and 3274 subjects without CRC (controls), from the Rhine-Neckar region of Germany from 2013 to 2010 was carried out.

Colonoscopy Reduces Colorectal Cancer Incidence in Older Individuals

To investigate whether sigmoidoscopy or colonoscopy is associated with a decreased incidence of colorectal cancer (CRC) in older individuals, and whether the effect of colonoscopy differs by anatomic locations, a case-controlled study was carried out using linked US Veterans Affairs and Medicare data.

Direct-Acting Antiviral Combination Medications Efficacy Against HCV Genotype 1 Infection

An all-oral regimen comprising the nucleotide polymerase inhibitor sofosbuvir (SOF) with the NS- 5A inhibitor ledipasvir (LDV) or the NS-5B non- nucleoside inhibitor GS 9669, was evaluated in patients with genotype 1 HCV infection.

Medical Bulletin Board


Foundation Champions Innovation & Collaboration to Accelerate IBD Breakthroughs


Katie Couric and the Entertainment Industry Foundation Launch Citywide "Make That Call" Campaign with NewYork-Presbyterian and its Jay Monahan Center for Gastrointestinal Health

Meetings Calendar

May 3-6, 2014 Digestive Disease Week - Exhibit Dates: May 4-6

May 17-21, 2014 ASCRS Annual Scientific Meeting

September 16, 2014 Raising C Diff Awareness Conference