July 2015 Vol XXXIX Issue 7
INFLAMMATORY BOWEL DISEASE: A PRACTICAL APPROACH, SERIES #95
The Gut Microbiome - Clinical Implications for the Practicing GastroenterologistThese are exciting times in microbiome research. In this article, we discuss a field that simply did not exist a few years ago and has exponentially expanded to become one of the hottest in all of biomedicine. As techniques develop, become more rapid and less costly, the delineation of the true extent of the role of our bacterial fellow travelers in health will soon be realized.
FRONTIERS IN ENDOSCOPY, SERIES #20
Diagnosis and Management of Barrett's EsophagusUnderstanding of the underlying histology and pathogenesis of Barrett’s Esophagus, has led to the creation of several new tools aimed at improving detection rates and yielding better patient prognoses. This review will describe the most current diagnostic techniques and treatment options of Barrett’s Esophagus and early esophageal cancer, their basic risks and benefits, and their clinical applicability.
NUTRITION ISSUES IN GASTROENTEROLOGY, SERIES #143
Low Residue vs. Low Fiber Diets in Inflammatory Bowel Disease: Evidence to Support vs. Habit?Despite lack of evidence to support the practice, IBD patients are often instructed to limit fiber or residue during active flares to reduce gastrointestinal distress. The same advice is common when intestinal strictures are identified or suspected, to reduce the risk of obstruction. Low residue and low fiber diets are often recommended interchangeably, although they comprise two distinct diets. This review discusses the similarities and differences between “residue” and “fiber” and presents the studies that have evaluated the use of low residue and low fiber diets in IBD.
A SPECIAL ARTICLE
The Complications of Diabetes in the Gastrointestinal TractDiabetes and hyperglycemia have immediate and long term effects in the gastrointestinal (GI) tract. In this article, we comprehensively review the complications of diabetes in the gastrointestinal tract including oral and esophageal candidiasis, gastroesophageal reflux disease (GERD), esophageal dysmotility, gastroparesis, small intestinal bacterial overgrowth, diarrhea and nonalcoholic fatty liver disease (NAFLD). We also describe the increased risk of GI malignancies in these patients.
A CASE REPORT
A Rare Presentation of a Common Condition: A Squamous Cell Papilloma Causing Dysphagia and HematemesisFELLOWS' CORNER
Fellows' CornerDepartments Section
To determine the natural history of small subepithelial tumors (SELs), less than 30 mm in size after evaluation by EUS, surveillance was carried out to determine degree of patient compliance with surveillance recommendations in a prospective registry at two tertiary centers, including 187 consecutive adult patients referred for EUS evaluation of foregut cells.
Surveillance of Small Upper Gastrointestinal Subepithelial Tumors
An open-label trial was conducted to assess the efficacy and safety of ledipasvir (LDV-SOF), plus RBV in patients with genotype 1 HCV who did not achieve SVR after treatment in phase II and III trials of SOF regimens.
Treatment of Patients With Failed Prior Treatment in Clinical Trials of Sofosbuvir Regimen for Genotype 1 HCV
The risk of peptic ulcer bleeding (PUB) associated with the interaction of NSAIDs and including low-dose aspirin (ASA) with H. pylori infection was evaluated in this study to determine the risk with their interactions.
Bleeding Peptic Ulcer, NSAIDs and H. Pylori
A study was carried out aiming to evaluate local recurrence and its associated risk factors after endoscopic resection (ER) for colorectal neoplasia 2 cm or greater in size.
Local Recurrence of Colorectal Neoplasia
A multi-center, phase III trial evaluated oral lubiprostone for constipation associated with non-methadone opioids in patients with chronic noncancer-related pain.
Lubiprostone for Opioid-Induced Constipation in Chronic Non-Cancer Pain
Recently, several drugs were reported to increase the risk of microscopic colitis (MC) and this study characterized that presentation as chronic, watery diarrhea.
Drug-Induced Microscopic Colitis
The editors and authors of this scholarly collection are truly an all-star cast of internationally renowned experts. Together they have attempted to tackle the challenge of covering the vast subject of neurogastroenterology, including both functional and gastrointestinal (GI) motility disorders, in a succinct and clinically focused manner.
Functional and GI Motility Disorders
Whether you're heading out for a couple weeks or even just a long weekend, if you’re a hemorrhoid sufferer you need to be prepared for flare ups that may happen at the most inopportune times!
WE ALL HAVE BAGGAGE, BUT YOURS JUST GOT LIGHTER...INTRODUCING NEW RECTICARE® MEDICATED ANORECTAL WIPES
INVESTIGATORS SHOW HOW IMMUNE CELLS ARE EDUCATED NOT TO ATTACK BENEFICIAL BACTERIA
WEILL CORNELL INVESTIGATORS DISCOVER A NEW PATHWAY THAT PREVENTS CHRONIC INFLAMMATION IN THE GUT
WHOLE GRAINS MAY BENEFIT YOUR HEART AND LENGTHEN YOUR LIFE, FROM THE APRIL 2015 HARVARD HEART LETTER
Boston, MA - Foods made from whole grains, the hard, dry seeds of plants, have been a nutritional staple for thousands of years. They provide a wealth of heart- healthy nutrients, including fiber, vitamins, minerals, good fats, enzymes, antioxidants, and phytonutrients, according to the April 2015 Harvard Heart Letter.