September 2015 Vol XXXIX Issue 9

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Medicinal Plants Used for Digestive Disorders – What the Gastroenterologist Needs to Know

Armando Enrique Gonzalez-Stuart, Richard W. McCallum

Medicinal plants have been used by all cultures throughout history and still continue to be an integral part of our modern civilization. From generation to generation, various ethnic groups around the world have used a wide array of plants to treat various gastrointestinal problems. With the remarkable surge of so-called complementary and alternative medicine, or CAM (currently known by the more accurate term of Integrative Medicine), it is imperative that the gastroenterologist be aware of both the potential risks as well as the benefits of using herbal medicine in his/her modern practice.


D-Lactic Acidosis: More Prevalent Than We Think?

Luke White

D-lactate acidosis, in which the D-isomer of lactate accumulates, is a disorder that has been reported in the setting of short bowel syndrome, and in particular, with high carbohydrate diets in children. In this article, we present information about D-lactate that will increase the readers' level of vigilance for this disorder, which affects a broader group of patients than initially thought.


A Review of the Relationship Between Inflammatory Bowel Disease and Vitamin D

Shail M. Govani, Peter D.R. Higgins

There is increasing interest in the role of vitamin D in autoimmune diseases. Among patients with inflammatory bowel disease (IBD), a significant percentage are vitamin D deficient. It remains unclear whether this deficiency is related to the disease or is rather a result of malabsorption from the disease. The main driver of vitamin D levels, UV exposure, has been linked to decreased risk of inflammatory bowel diseases by epidemiological studies. Here, we will review the evidence linking vitamin D to inflammatory bowel diseases.


Single Balloon Enteroscope for Complete Colonic Examination in Patients with Failed Colonoscopy

Kimberly Kolkhorst, Eric Hill, Patrick Brady

Colonoscopy is the current gold standard for colorectal cancer screening; however 5-10% of colonoscopies performed are incomplete. If the cecum cannot be intubated, a full diagnostic evaluation has not been achieved. Standard options to complete the evaluation include air contrast barium enema, CT colonography, or repeat colonoscopy. In this article, we present our study of the use of a single balloon enteroscope (SBE) to reach the cecum as an alternative method for complete colonic examination in patients failing conventional colonoscopy.


Ampullary Carcinoid as a Rare Cause of Acute Relapsing Pancreatitis

John M. Petersen, David H. Holloman

Departments Section

Book Reviews

Pediatric Nutrition in Practice (World Review of Nutrition and Dietetics, Vol. 113), 2nd Edition

This book was written by an international panel of pediatric nutrition experts and is formatted into short and tightly constructed chapters on all aspects of pediatric nutrition.

Acing the GI Board Exam: The Ultimate Crunch Time Resource

Have you ever noticed that everyone seems to be an expert on what is on the board exam? I wish I had a dollar for every time I heard an academic physician say “you better know that because it’s going to be on your board exam”. The problem is that they are usually wrong.

From the Literature

Risk of Reactivation of Prior-Resolved HBV in Rheumatologic Therapy

To assess the safety of different immunosuppressive biologic therapy, including rituximab, anti-tumor necrosis factor-alpha, and other biologic therapies, a total of 1218 Caucasian rheumatologic patients admitted consecutively as outpatients between 2001 and 2012 were studied.

Fructose and NAFLD

To examine the cross-sectional association between intake of sugar-sweetened beverages or diet soda and fatty liver disease in participants of the Framingham offspring and third generation cohorts, liver attenuation measurements generated from computed tomography at 2634 participants was carried out to define fatty liver disease.

Hepatic Steatosis and Cardiovascular Disease Outcomes

To examine the association of hepatic steatosis with prevalent clinical and subclinical CVD outcomes in a large, community-based sample and Framingham Heart Study, hepatic steatosis was measured in 3529 participants using multidetector computed tomography scanning.

Sarcopaenia and NAFLD

To investigate the direct relationship between sarcopaenia and NAFLD or steatohepatitis in the general population, a cross-sectional study using nationally representative samples of 15,132 subjects from the Korean National Health and Nutrition Examination Surveys from 2008 to 2011 was carried out.

From the Pediatric Literature

Glutathione, Growth, and Cystic Fibrosis

Malnutrition is a common problem in patients with cystic fibrosis (CF), and this issue is especially concerning in the pediatric population. Oral reduced glutathione has been demonstrated to be an important source of energy for enterocytes with potential antioxidant properties, and the authors of this study studied if glutathione use (specifically oral reduced glutathione) could improve growth in children with CF.

Cystic Fibrosis and the Microbiome

Cystic fibrosis (CF) is associated with abnormal bacterial profiles in both the lungs and intestines. This study evaluated the effect of intestinal bacterial diversity in pediatric patients with CF in relation to their lung health.

Medical Bulletin Board


BETHESDA, MD - The American Gastroenterological Association (AGA), the leading voice of the gastrointestinal community, today released the findings of a national survey of gastroenterologists on biologics and biosimilars.


SonarMD, LLC, recently announced the release of its SonarMD Platform, a first-of-its kind, cloud-based algorithmic process for securely engaging, monitoring and managing patients with chronic gastrointestinal disease.

Meetings Calendar

October 16-21, 2015 American College of Gastroenterology Annual Meeting
November 13-17, 2015 The Liver Meeting® 2015
December 10-12, 2015 - 2015 Advances in Inflammatory Bowel Diseases, Crohn's & Colitis Foundation's Clinical & Research Conference