September 2016 Vol XL Issue 9

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COLORECTAL CANCER: REAL PROGRESS IN DIAGNOSIS AND TREATMENT, SERIES #7

A Colonoscopist's Perspective on Serrated Lesions

Douglas K. Rex

A full understanding of the spectrum of endoscopic appearances, as well as methods of effective resection, are essential to modern colonoscopic management of serrated lesions and to effective colonoscopy. Current recommendations for surveillance colonoscopy after resection of serrated are based on limited data, and are reviewed in this paper.



A SPECIAL ARTICLE

Predictors of Gastroesophageal Refux Disease Evidence in Noncardiac Chest Pain: A New Management Algorithm

Alexandra Baumann, David Wheeler, Monil Patel, Stacey Zavala, Philip O. Katz

In order to identify a cost-effective, organized approach to managing NCCP, we aimed to identify clinical predictors of objective evidence of GERD on endoscopy in order stratify patient risk and optimize utilization of EGDs and PPI trials in this population.



FRONTIERS IN ENDOSCOPY, SERIES #29

EUS-Guided Liver Biopsy: An Emerging Diagnostic Modality

Kirby Mengert, Douglas G. Adler

A new method of collecting liver histology is via endoscopic ultrasound (EUS) guided liver biopsy which allows the endoscopist to obtain the necessary liver histology while theoretically limiting complications for the patient. In this article we discuss EUS guided liver biopsy as a viable and safe means for assessing liver histology.



GERD IN THE 21ST CENTURY, SERIES #25

Achalasia: Common Features of an Uncommon Disease

Mohamed Khalaf, Donald Castell

Primary achalasia is a rare worldwide disease with prevalence of eight cases per million population. Manometry is considered the gold standard for diagnosis. Achalasia is incurable in that no treatment can restore the neuronal degeneration; therefore, therapy is aimed at opening the poorly relaxed LES. Here we review the evidence which shows that pneumaticdilation (PD) and surgery are equally effective, with PD having a slight edge. We believe that using PD as initial therapy and saving myotomy as a rescue approach is the preferred overall approach.



NUTRITION ISSUES IN GASTROENTEROLOGY, SERIES #155

Refeeding the Malnourished Patient: Lessons Learned

Stacey McCray, Carol Rees Parrish

Symptoms of Refeeding Syndrome (RS) can vary from a mild fall in serum electrolytes to critical electrolyte disarray and even death in the most severe cases. The goals of this article are to help clinicians better understand the mechanism of RS, recognize patients at risk, and identify the clinical circumstances that may require special attention.



GASTROINTESTINAL MOTILITY AND FUNCTIONAL BOWEL DISORDERS, SERIES #19

Rumination Syndrome: An Update on Diagnostic and Treatment Strategies

Mena Milad, Richard W. McCallum

Rumination syndrome (RS) can occur as a primary disorder or as a conditioned response in the setting of other vomiting disorders, particularly gastroparesis. This article will focus on the importance of history taking to diagnose rumination syndrome and review treatment strategies including breathing and relaxation skills. In addition, we emphasize a new approach, jejunostomy tube placement in patients with the most severe symptoms.



A CASE REPORT

Endoscopic Pyloromyotomy for the Treatment of Benign Pyloric Stenosis

Kimberly J. Kolkhorst, Jeffrey Gill



Departments Section


Book Reviews

Barrett's Esophagus: Emerging Evidence for Improved Clinical Practice

This is a well-written book that summarizes in a very succinct way the most up-to-date knowledge about Barrett's esophagus and gives an excellent overview of current and future clinical management of this disease.



From the Literature

Risk of HCC After SVR in Veterans With HCV

The long-term prognosis in terms of risk or predictors of developing HCC among patients with SVR remains unclear.



Treatment with Immune Suppressive Therapy in Patients with Cancer

To determine the safety of immunosuppressive therapy for patients with immune-mediated diseases and a history of a malignancy, MEDLINE, EMBASE and conference proceedings for terms related to immune- mediated disease, immune suppressive therapy, and cancer recurrence from inception to April 2015 were searched.



Statins in the Treatment of HCV Cirrhosis

Statins are associated with delayed brosis progression and a reduced risk of hepatocellular carcinoma (HCC) in chronic HCV. Limited data exists regarding the most effective type and dose of statin in this population.



Treatment of HCV with Portal Hypertension and Cirrhosis

To evaluate the benefit of SVR in patients with HCV and cirrhosis without (stage 1) and with (stage 2) esophageal varices (EV), a prospective cohort study was performed of 444 patients with HCV and compensated cirrhosis (218 with stage 1 and 226 with stage 2 disease), treated with PEG-Interferon and Ribavirin from June 2001 through December 2009...



From the Pediatric Literature

Visualizing the Small Bowel in Pediatric Gastroenterology

Adult gastroenterologists have signi cantly more experience compared to pediatric gastroenterologists in the use of video capsule endoscopy (VCE) and double balloon enteroscopy (DBE) used in the detection and potential treatment of mucosal lesions involving the distal small intestine. The authors of this study performed a single- center, retrospective review of 36 pediatric patients (age range 5-20 years) who had undergone both VCE and DBE...



Can We Predict Which Adults Will Get Fatty Liver Based on Childhood Risk Factors?

Non-alcoholic fatty liver disease (NAFLD) is associated with obesity, and the authors of this study evaluated childhood risk factors that subsequently could lead to fatty liver disease in adults.



Medical Bulletin Board

LISA TRACKER® CHOSEN BY JANSSEN BIOTECH FOR ITS PROGRAM TO MONITOR PATIENTS TREATED WITH REMICADE® IN THE USA

CROISSY-BEAUBOURG and MONTPELLIER - THERADIAG (ISIN: FR0004197747, Ticker: ALTER, PEA-PME eligible), a company specialized in in vitro diagnostics and theranostics, reports that, on August 29, Janssen Biotech Inc. announced the launch of a program to offer free monitoring tests to help healthcare professionals (HCP) better use Remicade® in treating patients with inflammatory bowel disease (IBD).



INVENDO MEDICAL ANNOUNCES FDA CLEARANCE OF THE INVENDOSCOPY E200 SYSTEM – INCLUDING THE FIRST AND ONLY STERILE, SINGLE-USE ENDOSCOPE FOR COLONOSCOPIES

NEW YORK and KISSING, Germany (GLOBE NEWSWIRE) - invendo medical GmbH, a leading developer and distributor of sterile, single-use and robotically-assisted HD endoscopy products in the eld of gastroenterology and GI surgery, today announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for the invendoscopy E200 System...



Meetings Calendar

American College of Gastroenterology Annual Meeting - October 14-19, 2016
December 8-10, 2016 Advances in Inflammatory Bowel Diseases Crohn's & Colitis Foundation's Clinical & Research Conference
February 19-22, 2017 - The GUILD Conference