November 2017 Vol XLI Issue 11

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NUTRITION ISSUES IN GASTROENTEROLOGY, SERIES #169

A Clinician's Guide to Defining, Identifying and Documenting Malnutrition in Hospitalized Patients

Wendy Phillips, Maria Browning

As our understanding of the effects of malnutrition on outcomes and hospital stays has evolved, it has become increasingly important for the Registered Dietitian Nutritionist (RDN) to consistently identify and communicate the degree of malnutrition present in any patient who meets criteria, in order to set up a timely treatment plan. The clinical nutrition team is positioned to spearhead the education of all appropriate providers to ensure consistent use of the approved criteria throughout the facility. This article aims to provide practical guidance for clinicians to do just that.



DISPATCHES FROM THE GUILD CONFERENCE, SERIES #9

Treatment of Hepatitis C in Patients with Compensated and Decompensated Cirrhosis

Elie Ghoulam, Nancy Reau

Hepatitis C virus (HCV) treatment of compensated and decompensated cirrhosis differs because of the marginal hepatic function, increased mortality and high risk of complications in decompensated cirrhosis. Before the development of oral direct acting antivirals (DAAs), treating patients with decompensated cirrhosis was not an option. This article will address the management, the most recent recommended treatment and post cure monitoring of patients with compensated and decompensated HCV cirrhosis.



FRONTIERS IN ENDOSCOPY, SERIES #40

EUS-Guided Fiducial Placement - Role and Use in Clinical Practice

Douglas G. Adler

Fiducial markers are used throughout medicine as a means of precisely localizing structures for diagnosis, treatment, imaging and other uses. In gastroenterology, fiducial markers are almost always placed via EUS, which allows precise placement of fiducial markers. In this article, we discuss the history, effectiveness and safety of the use of EUS guided fiducial placement to help precisely target therapy.



A CASE REPORT

Complicated Metastatic Melanoma to the Gastrointestinal Tract

Joseph P. Kingsbery, David M. Poppers



Departments Section


From the Literature

Reactivation of Hepatitis B with Chemotherapy

Because of conflicting studies in reference to whether the antibody to hepatitis B surface antigen (anti- HBs), protects against reactivation in patients with resolved hepatitis B infection receiving chemotherapy for hematological malignancies, a meta-analysis was conducted to determine if anti-HBs reduces HBV reactivation risk.



Low-Level HBV Viremia and Risk of Hepatocellular Carcinoma

To determine whether the development of low-level viremia (LLV - less than 2 iu/mL) during entecavir monotherapy requires a change in therapy, a retrospective cohort of 875 treatment-nai?ve, chronic HBV monoinfected patients who received Entecavir monotherapy were analyzed for development of hepatocellular carcinoma (HCC).



Fundic Gland Polyps with Dysplasia

While fundic gland polyps (FGPs) rarely exhibit dysplasia of the surface epithelium, that circumstance is felt to be a strong marker for familial adenomatous polyposis (FAP), although sporadic, non-syndromic FGPDs also occur.



Adenoma Detection Rate and Risk of CRC and Death

To investigate whether increasing adenoma detection rate (ADR) from individual endoscopists is associated with reduced risk of interval colorectal cancer and subsequent death, a prospective cohort study of individuals who underwent a screening colonoscopy within the National Colorectal Cancer Screening Program in Poland, from 1/1/2014 through 12/31/2008 was carried out.



Annual Risk of Esophageal Adenocarcinoma in Barrett's Esophagus

To investigate the risk of esophageal adenocarcinoma (EAC) in Barrett's esophagus (BE) patients in relationship to number of success of endoscopies, years of follow-up and calendar year, a retrospective cohort study of male veterans with newly diagnosed BE during 2004 to 2009 with follow-up until 9/30/2011 was carried out.



POEM in Treatment of Achalasia

The safety of per oral endoscopic myotomy (POEM) was evaluated for safety considerations, studying the prevalence of adverse events (AEs), and factors associated with occurrence of AEs in patients undergoing that procedure at 12 tertiary care centers between 2009 and 2015.



HCC in HCV Patients Treated with Direct-Acting Antiviral Agents

To examine the risk and determinants of HCC in patients cured with direct-acting antivirals (DAA), a retrospective cohort study was conducted of HCV patients who were treated with DAA in any of the 129 Veterans Health Administration hospitals between 1/1/2015 and 12/31/2015.



Proton Pump Inhibitor Use and Cognitive Function in Women

Because of reported association between PPI use and dementia, associations between proton pump inhibitor use and performance were examined in tests of cognitive function. Associations for H2 receptor antagonists (H2RAs), were added to the study as a secondary aim.



From the Pediatric Literature

Dietary Therapy as Treatment for Pediatric Crohn Disease

Exclusive enteral nutrition (EEN) is a potential intervention for pediatric Crohn disease (CD). One such diet involves the speci c carbohydrate diet (SCD) which excludes grain products, processed food, and dairy while adding in nuts, nut our, fermented yogurt, and honey.



From the Literature

Narrow-Band Imaging for Gastric Intestinal Metaplasia

To compare detection of gastric intestinal metaplasia (GIM) with high-de nition white-light (HD-WL) endoscopy, NBI and mapping biopsies were carried out in a population with increased gastric cancer risk.



From the Pediatric Literature

Probiotics and Child Care Facilities

Children in childcare facilities (such as daycare) have an increased risk of gastrointestinal infections due to exposure to other sick children. Probiotics can be used to potentially alter the intestinal microbiome, and the authors of this study examined the effect of probiotic use in preventing gastrointestinal and respiratory infections in young children attending childcare in Denmark.



Medical Bulletin Board

COMPULINK SHOWCASES BEST-OF-BREED TECHNOLOGY FOR GASTROENTEROLOGISTS AT ACG 2017

MACRA-ready All-in-One solution includes unique OneTab™ EHR to streamline physician work ow and report writer replacement for Olympus EndoWorks



NEW META-ANALYSIS PROVIDES A COMPREHENSIVE VIEW OF REAL-WORLD DATA AND FURTHERS UNDERSTANDING OF ENTYVIO AS AN IMPORTANT TREATMENT OPTION FOR PATIENTS WITH ULCERATIVE COLITIS OR CROHN'S DISEASE

Takeda Pharmaceutical Company Limited (TSE: 4502) (Takeda) announced the presentation of real-world evidence from two analyses evaluating the safety pro le of Entyvio&req; (vedolizumab), during the 25th United European Gastroenterology (UEG) Week in Barcelona, Spain (October 28-November 1).



SALIX PHARMACEUTICALS ADDRESSES IBS-D AT WCOG

In an effort to educate and open a dialogue between healthcare providers and patients about irritable bowel syndrome with diarrhea (IBS-D), Salix Pharmaceuticals partnered with Access Health on Lifetime Television to develop a segment bringing attention to this issue.



THE CROHN'S & COLITIS FOUNDATION INVITES YOU TO JOIN US AND TAKE STEPS FOR CURES

Walk With Our IBD Community!



FINDINGS OF NIH-FUNDED PILOT STUDY SUGGEST HOME-DELIVERED NUTRITIONAL MEALS MAY LOWER PATIENT READMISSION RATES AND IMPROVE HEALTH OUTCOMES

November, 2017 - Des Moines, IA. New findings from a pilot clinical trial, GOURMET-HF (Geriatric Out-of-Hospital Randomized Meal Trial in Heart Failure), suggest that the delivery of low-sodium prepared meals to patients' homes following hospital discharge resulted in fewer instances of readmission and generally improved health outcomes.



Meetings Calendar

December 14-15, 2017 - The New York Society for Gastrointestinal Endoscopy 41st Annual New York Course - Precision Endoscopy - The Scope of the Future
Jan. 18-20, 2018 - The Crohn's & Colitis Congress
February 11-14, 2018 - The 2nd Annual The GUILD Conference 2018
May 19 - 23, 2018 - The 2018 American Society of Colon and Rectal Surgeons (ASCRS) Annual Scientific Meeting
June 2-5, 2018 - Digestive Disease Week (DDW)