June 2017 Vol XLI Issue 6
INFLAMMATORY BOWEL DISEASE: A PRACTICAL APPROACH, SERIES #101
Clostridium difficile Infection in Inflammatory Bowel Disease An Updated ReviewThe incidence and severity of Clostridium difficile infection (CDI) is rising, primarily due to a new and virulent strain. Unlike patients in the general population, those with IBD who acquire C. difficile tend to be younger, have less antibiotic exposure and have more community-acquired infections. Given the high burden of CDI in IBD patients who have an acute IBD flare, all patients should be tested for CDI. Treatment of CDI focuses on antibiotics, however, in IBD patients, attention is required regarding immunosuppression during treatment. The aim of this paper is to review the most updated information on CDI in IBD including the epidemiology, pathogenesis, clinical presentation, risk factors, diagnosis and treatment guidelines.
NUTRITION ISSUES IN GASTROENTEROLOGY, SERIES #164
Essential Fatty Acid DeficiencyEssential fatty acid deficiency (EFAD) may occur in both the inpatient and outpatient setting. Patients with malabsorptive disorders as a result of pancreatic insufficiency or massive bowel resection are at risk, and it is important to recognize that other patient populations may develop EFAD. A relatively new risk factor for EFAD is the shortage of intravenous fat emulsions in those requiring parenteral nutrition. This article provides a brief review of the role of essential fats, identifies those at risk, the clinical signs and symptoms associated with EFAD, as well as prevention and treatment recommendations.
DISPATCHES FROM THE GUILD CONFERENCE, SERIES #5
Postoperative Management of Crohn’s DiseaseThe majority of patients with Crohn's disease will require an intestinal resection at some point in their life. Postoperatively, these patients are at risk for developing recurrent Crohn’s disease and medications are often required to prevent recurrence. Here we discuss the importance of stratifying patients according to their risk of recurrence as it determines postoperative management.
A CASE REPORT
Familial Multifocal Gastrointestinal Stromal Tumors - Critical Lessons in Identification of a Rare DisorderDepartments Section
Endoscopic Submucosal Dissection for Superficial Colorectal Tumors
ESD is an effective procedure for en bloc resection of superficial colorectal tumors, regardless of tumor size or location. To evaluate long-term outcomes for patients with these tumors after ESD, evaluation of those outcomes long-term were evaluated in 257 colorectal tumors in 255 consecutive patients at Hiroshima University Hospital between June 2003 and July 2010.
Endoscopic Features of Ulcerative Colitis-Associated Dysplasia
Recent advances in endoscopic equipment and diagnostic techniques have made possible the detection of early dysplasia in the inflamed mucosa of ulcerative colitis (UC), The SENIC Consensus Statement recommends the use of unified terminology for the morphology of dysplasia.
Sessile Serrated Adenoma Polyp in HyperplasticAppearing Diminutive Rectosigmoid Polyps
The ASGE recommends that distal colon hyperplastic lesions can be left in place without resection if adenomatous histology can be excluded with greater than 90% negative predictive value.
Low-Grade Dysplasia in Barrett’s Esophagus
To analyze histopathologic criteria required for a diagnosis of low-grade dysplasia (LGD), using the new subcategories of LGD with inflammatory and dysplastic features, each diagnosis was categorized on the level of confidence and assessed intra-observer agreement among gastrointestinal pathologists from five tertiary centers in the United States and Europe.
Occult HCV in Reported Sustained Virologic Response To DAA for Recurrent Infection
After Liver Transplantation Occult infection with HCV is defined as the presence of HCV genome in either liver tissue or peripheral blood monocytes, despite constant negative results from tests for HCV RNA in serum to investigate whether patients who maintain an SVR 12 weeks after therapy (SVR 12) with direct-acting antiviral (DAA) agents for recurrent HCV infection after liver transplantation had occult HCV infections.
Outcome of Pregnancies When Interrupted by Endoscopic Evaluation
To examine outcomes of pregnancy for women who underwent endoscopy during their pregnancy, a nationwide, population-based cohort study was carried out linking data from the Swedish Medical Birth Registry (from 1992 through 2011), with those from the Swedish Patient Registry.
DIAGNOS-TECHS GASTROINTESTINAL HEALTH PANELS AND CALPROTECTIN
Gastrointestinal Health Panels Diagnos-Techs Regular and Expanded Gastrointestinal Health Panels (GI-1 and GI-2) include 15-22 separate screening tests to measure overall GI health and function. Stool and saliva samples are submitted by the patient after home collection.
FIRST PATIENTS AT VANDERBILT UNIVERSITY MEDICAL CENTER IMPLANTED IN ENDOSTIM’S LESS GERD CLINICAL TRIAL FOR GASTROESOPHAGEAL REFLUX DISEASE (GERD)
NASHVILLE, TN and DALLAS, TX - Vanderbilt University Medical Center (VUMC) and EndoStim, Inc., announced that the first patients in Nashville, Tennesse have been implanted with the EndoStim device in the Lower Esophageal Sphincter Stimulation for GERD (LESS GERD) trial.
July 22, 2017 Mastering Clinical Challenges and Emerging Therapies in IBD
October 13-18, 2017 World Congress of Gastroenterology (WCOG) at ACG 2017
November 9-11, 2017 - Advances in Inflammatory Bowel Diseases - Multidisciplinary Approaches to IBD Patient - Centered Care New Presenters, New Content, A New Year
