January 2019 Vol XLIII Issue 1

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Dispatches from the GUILD Conference 2019

Uma Mahadevan


Eosinophilic Esophagitis: When to Suspect and Why to Treat with Proton Pump Inhibitors

Rhonda F. Souza

Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disease driven by food allergens that manifests with symptoms of esophageal dysfunction andeosinophil-predominate esophageal inflammation. Recent consensus guidelines now include proton pump inhibitor therapy as an alternative first-line treatment. This review will provide an overview of when to suspect and how to diagnosis EoE, concepts surrounding pathogenesis and increasing incidence of this newly recognized esophageal condition, and a discussion on why proton pump inhibitors are now being used as a first-line treatment strategy.


Part I Enteral Feeding Barriers: Pesky Bowel Sounds & Gastric Residual Volumes

Carol Rees Parrish, Stacey McCray

Enteral nutrition (EN) is an effective way to nourish patients; however, many barriers prevent consistent and effective delivery of EN in the hospitalized patient. Clinicians must focus on interventions that will make our patients comfortable while their EN is infusing. Part I of this four part series critically evaluates two of the most common barriers to EN: the use of bowel sounds to assess readiness for EN and gastric residual volumes to assess tolerance of EN. Strategies to manage such obstacles in the clinical setting will be provided.

Departments Section

From the Pediatric Literature

Do Risk Factors During Infancy Predict Eosinophilic Esophagitis?

Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus involving eosinophils and leading to esophageal damage, including fibrosis. EoE is increasing in prevalence, and although it is thought that food allergies may play a role in its pathogenesis, it is unknown if early infant exposures increase the risk of EoE. The authors of this study developed a case-control study using the United States military health system database (TRICARE Management Activity's Military Health System) which contains medical data on all service members and their families.

Infant Colic and Long-Term Outcomes

Infant colic is typically defined as excessive amounts of crying in the first 3 months of life. Many infants with colic are referred to pediatric gastroenterology as parents and providers often have concerns that there is a gastrointestinal cause for this condition although the potential association between gastrointestinal disorders and colic is debatable. It is also unclear as to the long-term outcome of infants with colic.

Meetings Calendar

February 7 - 9, 2019,Crohn's & Colitis Congress Transforming IBD Care
February 17-20, 2019 GUILD Conference 2019
March 23-26, 2019 ASPEN 2019 Nutrition Science & Practice Conference
April 5-7, 2019 Interdisciplinary Autoimmune Summit 2019